fatma
Address: İstanbul Teknik Üniversitesi Fen Edebiyat Fakültesi Moleküler Biyoloji ve Genetik Bölümü, Maslak 34469 İstanbul
Phone: +90 212 285 7246
Fax: +90 212 285 6386
E-mail: kokf@itu.edu.tr



Education and Experience

Prof.Dr. (2019- ) – Istanbul Technical University, Faculty of Science and Letters, Department of Molecular Biology and Genetics
Assoc.Prof.Dr. (2012-2019) – Istanbul Technical University, Faculty of Science and Letters, Department of Molecular Biology and Genetics
Assist.Prof.Dr. (2005-2012) – Istanbul Technical University, Faculty of Science and Letters, Department of Molecular Biology and Genetics
Postdoctoral Researcher (as Humboldt Fellow) (2003-2005)- Max Planck Institute for Polymer Research, Germany; Max Planck Institute for Biochemistry, Germany
Postdoctoral Researcher(2001-2003)- Middle East Technical University, Biotechnology, Ankara
Research Assistant(1996-2001) – METU Biotechnology, Ankara
Ph.D. (1997-2001) – METU Biotechnology, Ankara
Ms.D. (1995-1997) – METU Biotechnology, Ankara
BS.(1990-1994) – METU Chemical Engineering, Ankara


Research Interests

  • Immobilisation of biomolecules
  • Biosensors
  • Encapsulation and controlled release of bioactive agents
  • Biomaterial (metal and polymeric) and Tissue Engineering
  • Artificial Lipid Membranes



Publications (with ITU affiliation)

  1. A.Kılıç, F.N.Kök, Quartz crystal microbalance with dissipation as a biosensing platform to evaluate cell–surface interactions of osteoblast cells, Biointerphases 13, 011001 (2018)
  2. Z.Guler-Gokce, P.Akalın , F.N.Kok, A.S.Sarac, Impedimetric DNA biosensor based on Polyurethane/Poly(m-anthranilic acid) Nanofibers, Sensors & Actuators: B. Chemical, 254C (2018) pp. 719-726, 10.1016/j.snb.2017.07.136 http://www.sciencedirect.com/science/article/pii/S0925400517313515
  3. A.Kılıç, M.F. Jadidi, H.Ö.Özer, F.N.Kök, The effect of thiolated phospholipids on formation of supported lipid bilayers on gold substrates investigated by surface-sensitive methods, Colloids and Surfaces B: Biointerfaces, 160 (2017) 117-125
  4. G.G.Pekozer,M. Ramazanoglu, K.A.Schlegel, F.N.Kok and G.T.Kose, Role of STRO-1 sorting of porcine dental germ stem cells in dental stem cell-mediated bone tissue engineering, Artificial Cells, Nanomedicine, and Biotechnology, 2017, doi 10.1080/21691401.2017.1332637
  5. Ertan A.B., Kenar H., Beyzadeoglu T., F.N.Kok , Kose G.T., An in vitro human skeletal muscle model: coculture of myotubes, neuron-like cells, and the capillary network, Turk J Biol (2017) 41: doi:10.3906/biy-1611-22
  6. A. Kilic, F.N. Kok, Biomimetic Lipid Bilayers on Solid Surfaces: Models for Biological Interactions, Surface Innovations, 4(3): 141–157, DOI: 10.1680/jsuin.16.00008
  7. S. Önder, A.C. Calikoglu-Koyuncu, G.T. Kose, K. Kazmanli, F.N. Kok*, M. Urgen, Effect of magnesium and osteoblast cell presence on hydroxyapatite formation on (Ti,Mg)N thin film coatings, JOMJ-The Journal of The Minerals, Metals & Materials Society (TMS) JOM, 69(7), 1195-1205, 2017
  8. K. Bilir, M.-T. Weil, J. Lochead, F.N. Kok*, T. Werner, Construction of an oxygen detection based optic laccase biosensor for polyphenolic compound detection, Turkish Journal of Biology, 40: 1303-1310, 2016, doi:10.3906/biy-1602-40
  9. F. Inci, U. Celik, B. Turken, H.Ö. Özer, F.N. Kok, Construction of P-glycoprotein incorporated tethered lipid bilayer membranes, Biochemistry and Biophysics Reports, 2, 115–122, 2015
  10. H.Tezcan*, S. Oktug, F.N. Kok, Employing TDMA Protocol in Neural Nanonetworks in case of Neuron Specific Faults, IEEE Transactions on NanoBioscience, 14(6):572-580, 2015
  11. S. Önder, A.C. Calikoglu-Koyuncu, K. Kazmanli, M. Urgen, G.T. Kose*, F.N. Kok, Behavior of Mammalian Cells on Magnesium Substituted Bare and Hydroxyapatite Deposited (Ti,Mg)N Coatings, New Biotechnology, 32(6), 747–755, 2015DOI: 10.1016/j.nbt.2014.11.006
  12. G.Baysal*, S. Önder*, İ. Göcek, L. Trabzon, H. Kızıl, F. N. Kök and B.Karagüzel-Kayaoğlu, Design and Fabrication of a New Nonwoven-Textile Based Platform for Biosensor Construction, Sensors & Actuators: B. Chemical, 208, 475–484, 2015
  13. G.Baysal*, S. Önder*, İ. Göcek, L. Trabzon, H. Kızıl, F. N. Kök and B.Karagüzel-Kayaoğlu, Microfluidic Device on a Nonwoven Fabric: A Potential Biosensor for Lactate Detection, Textile Research Journal, 84(16): 1729-1741, 2014
  14. P.S. Gungor-Ozkerim, T. Balkan, G.T. Kose, A.S. Sarac, F.N.Kök, Incorporation of growth factor loaded microspheres into polymeric electrospun nanofibers for tissue engineering applications, Journal of Biomedical Materials Research: Part A (DOI: 10.1002/jbm.a.34857, 2013)
  15. S.Önder, F.N.Kök, K.Kazmanlı, M.Ürgen, Magnesium Substituted Hydroxyapatite Formation on (Ti,Mg)N Coatings Produced by Cathodic Arc PVD Technique, Materials Science and Engineering C, 33, 4337-42, 2013
  16. A.B. Ertan, P. Yılgor, B. Bayyurt, A.C. Çalıkoğlu, F.N. Kök, G.T. Kose, V. Hasirci, Effect of double growth factor release on cartilage tissue engineering, Journal of Tissue Engineering and Regenerative Medicine, 7:149-160, 2013
  17. E. Tastan, S. Onder, F.N.Kök, Immobilization of Laccase on Polymer Grafted Polytetrafluoraelthylene Membranes for Biosensor Construction, Talanta, 84: 524-530, 2011
  18. S. Onder, K. Kazmanlı, F.N.Kök, Alteration of PTFE Surface to Increase Its Blood Compatibility, J. Biomaterials Science: Polymer Ed, 22:1443–1457, 2011
  19. E.-K. Sinner, U.Reuning, F.N.Kök, B.Saccà, L.Moroder, W.Knoll and D. Oesterhelt, Incorporation of integrins into artificial planar lipid membranes: characterization by plasmon-enhanced fluorescence spectroscopy, Analytical Biochemistry, 333(2): 216-224, 2004
  20. F.N.Kök and V.Hasirci, Determination of binary pesticide mixtures by an acetylcholinesterase–choline oxidase biosensor, Biosensors and Bioelectronics, 19(7): 661-665, 2004
  21. F.N.Kök, F.Bozoglu and V.Hasirci, Construction of an acetylcholinesterase-choline oxidase biosensor for aldicarb determination, Biosensors and Bioelectronics, 17(6-7): 531-539, 2002
  22. F.N.Kök, F.Bozoglu and V.Hasirci, Immobilization of acetylcholinesterase and choline oxidase in/on pHEMA membrane for biosensor construction, Journal of Biomaterials Science Polymer Edition, 12(11): 1161-1176, 2001
  23. F.N.Kök, R.M.Wilkins, R.B.Cain, M.Y.Arica, G.Alaeddinoglu and V.Hasirci, Controlled release of aldicarb from a lignin loaded ionotrophic hydrogel, Journal of Microencapsulation, 16(5): 613-623, 1999
  24. F.N.Kök, M.Y.Arica, O.Gencer, K.Abak and V.Hasirci, Controlled Release of aldicarb from carboxymethylcellulose microspheres; in vitro and field applications, Pesticide Science, 55:1194-1202, 1999
  25. F.N.Kök, M.Y.Arica, C.Halicigil, G.Alaeddinoglu and V.Hasirci, Biodegradation of aldicarb in a packed bed reactor by immobilized Methylosinus, Enzyme and Microbial Technology, 24:291-296, 1999
  26. M.Y.Arica, M.Yigitoglu, M.Lale, F.N.Kök and V.Hasirci, Controlled release of aldicarb from carboxymethylcellulose microcapsules, Turkish Journal of Chemistry, 21(2): 100-104, 1997